Drug Updates
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Drug Updates highlights information about new and revised products available in Canada that are coming to e-CPS. It includes new molecular entities, new products or products with major changes (new indications, new dosage forms, new formulations and reinstated products). New product information can also be found under What's New on the Home tab.

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Brand Name Generic Name Manufacturer Classification New Information Date Entered
ACET acetaminophen PendoPharm Analgesic - Antipyretic New product 09/01/2010
Bi-PegLyte bisacodyl/electrolytes/PEG 3350 PendoPharm Gastrointestinal lavage New product 09/01/2010
Cimzia certolizumab pegol UCB Biological response modifier New safety information: in the warnings and precautions, and adverse reactions sections 09/01/2010
Exelon rivastigmine hydrogen tartrate Novartis Pharmaceuticals Cholinesterase inhibitor New safety information: in the adverse reactions section 09/01/2010
Exelon Patch 5, Exelon Patch 10 rivastigmine Novartis Pharmaceuticals Cholinesterase inhibitor New safety information: in the adverse reactions section 09/01/2010
Famvir famciclovir Novartis Pharmaceuticals Antiviral agent New safety information: in the adverse reactions section 09/01/2010
Fosamax alendronate sodium Merck Frosst Bone metabolism regulator New safety information: in the adverse reactions section 09/01/2010
Fosavance alendronate sodium/cholecalciferol Merck Frosst Bone metabolism regulator and vitamin D New safety information: in the adverse reactions section 09/01/2010
Gardasil quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine Merck Frosst Active immunizing agent New indication: for boys and men 9 through 26 years of age for the prevention of infection caused by HPV types 6, 11, 16, and 18 and genital warts caused by HPV types 6 and 11 09/01/2010
Habitrol nicotine transdermal system Novartis Consumer Health Smoking cessation aid Product reinstated 09/01/2010
Invega Sustenna paliperidone palmitate Janssen-Ortho Antipsychotic agent New product: extended-release injectable suspension 09/01/2010
Methotrexate Injection USP methotrexate sodium Hospira Antimetabolite - Antirheumatic agent New full monograph, previously availability only 09/01/2010
Methotrexate Tablets USP methotrexate sodium Hospira Antimetabolite - Antirheumatic agent New full monograph, previously availability only 09/01/2010
Precedex dexmedetomidine HCl Hospira Alpha2-adrenergic agonist New molecular entity 09/01/2010
Rapamune sirolimus Wyeth Canada Immunosuppressive agent New safety information: in the adverse reactions section 09/01/2010
Alimta pemetrexed disodium Lilly Antineoplastic New indication: maintenance treatment of locally advanced or metastatic nonsquamous non-small cell lung cancer, in good performance status patients without disease progression immediately following four cycles of first-line platinum doublet chemotherapy, excluding pemetrexed 08/15/2010
Alimta pemetrexed disodium Lilly Antineoplastic New safety information: in the adverse reactions section 08/15/2010
Aredia pamidronate disodium Novartis Pharmaceuticals Bone metabolism regulator New safety information: in the warnings and precautions, and adverse reactions sections 08/15/2010
Casodex bicalutamide AstraZeneca Nonsteroidal antiandrogen New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Cialis tadalafil Lilly cGMP-specific phosphodiesterase type 5 inhibitor New safety information: in the adverse reactions section 08/15/2010
Clolar clofarabine Genzyme Antineoplastic agent New molecular entity 08/15/2010
Effexor XR venlafaxine HCl Wyeth Canada Antidepressant - Anxiolytic New safety information: in the adverse reactions section 08/15/2010
Humatrope somatropin Lilly Growth stimulant New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 08/15/2010
Invanz ertapenem sodium Merck Frosst Antibiotic New safety information: in the adverse reactions section 08/15/2010
Paxil paroxetine HCl GlaxoSmithKline Antidepressant - Antiobsessional - Antipanic - Anxiolytic - Social phobia (social anxiety disorder) - Post-traumatic stress disorder New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Paxil CR paroxetine HCl GlaxoSmithKline Selective serotonin reuptake inhibitor New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Pepto-Bismol with InstaCool bismuth subsalicylate Procter & Gamble Diarrhea relief - Heartburn relief - Indigestion relief - Nausea Relief - Upset stomach relief New product 08/15/2010
Rifadin rifampin sanofi-aventis Antibiotic New safety information: in the adverse reactions section 08/15/2010
Sandoz Atorvastatin atorvastatin calcium Sandoz Lipid metabolism regulator New product 08/15/2010
Sandoz Azithromycin Powder for Oral Suspension azithromycin monohydrate Sandoz Antibioitic New product 08/15/2010
Sandoz Fentanyl Patch fentanyl Sandoz Opioid analgesic New product 08/15/2010
Sandoz Naratriptan naratriptan HCl Sandoz 5-HT1 receptor agonist - Migraine therapy New product 08/15/2010
Sandoz Olanzapine ODT olanzapine Sandoz Antipsychotic New product 08/15/2010
Silkis calcitriol Galderma Topical non steroidal antipsoriatic agent New product 08/15/2010
Stelara ustekinumab Janssen-Ortho Biological response modifier New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Volibris ambrisentan GlaxoSmithKline Endothelin receptor antagonist New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Xatral alfuzosin HCl sanofi-aventis Adjunctive therapy in acute urinary retention (AUR) - Symptomatic treatment of benign prostatic hyperplasia (BPH) New safety information: in the adverse reactions section 08/15/2010
Zoladex goserelin acetate AstraZeneca Luteinizing hormone-releasing hormone (LHRH) analog New safety information: in the adverse reactions section 08/15/2010
Zoladex LA goserelin acetate AstraZeneca Luteinizing hormone-releasing hormone (LHRH) analog New safety information: in the adverse reactions section 08/15/2010
Dexilant dexlansoprazole Takeda Proton pump inhibitor New molecular entity 08/15/2010
Menveo meningococcal (groups A, C, Y and w-135) oligosaccharide corynebacterium diphteriae CRM197 conjugate vaccine Novartis Active immunizing agent New product 08/15/2010
Gadovist gadobutrol Bayer Contrast enhancement agent for magnetic resonance imaging (MRI) New indication: expansion of the conditions for use to pediatrics aged 2-17 years of age 08/15/2010
Humatrope somatropin Lilly Growth stimulant New indication: for the treatment of growth failure in children born small for gestational age (birth weight and/or length below - 2 SD) and who fail to achieve catch-up growth by 2 to 4 years or later 08/15/2010
PMS-Risedronate risedronate sodium hemi-pentahydrate Pharmascience Bone metabolism regulator New product 08/15/2010
ratio-Risedronate risedronate sodium hemi-pentahydrate ratiopharm Bone metabolism regulator New product 08/15/2010
Rituxan rituximab Roche Antineoplastic Addition to the Rheumatoid Arthritis (RA) indication: Rituxan in combination with Methotrexate has been shown to reduce the rate of progression of joint damage as measured by x-ray 08/15/2010
Tasigna (issued under NOC/C policy) nilotinib hydrochloride monohydrate Novartis Pharmaceuticals Protein-tyrosine kinase inhibitor New indication: For the treatment of chronic phase Philadelphia chromosome positive chronic myeloid leukemia (CML) in adult patients resistant to or intolerant of at least one prior therapy including Imatinib 08/15/2010
Agrylin anagrelide HCl Shire Platelet-reducing agent New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Arava leflunomide sanofi-aventis Antirheumatic - Immunomodulator agent New safety information: in the adverse reactions section 08/15/2010
Canesoral fluconazole Bayer Consumer Care Antifungal agent New product and schedule change: 150 mg single tablet now available without a prescription 08/15/2010
Canesoral Combi-Pak clotrimazole/fluconazole Bayer Consumer Care Antifungal agents New product and schedule change: 150 mg single tablet now available without a prescription 08/15/2010
Clavulin amoxicillin/clavulanic acid GlaxoSmithKline Antibiotic - β-lactamase inhibitor New safety information: in the warnings and precautions section 08/15/2010
Lantus insulin glargine (rDNA origin) sanofi-aventis Antidiabetic agent New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Livostin Eye Drops levocabastine HCl Novartis Pharmaceuticals Histamine H1-antagonist New safety information: in the adverse reactions section 08/15/2010
Lyrica pregabalin Pfizer Analgesic agent New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Nasacort AQ triamcinolone acetonide sanofi-aventis Corticosteroid New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Prezista darunavir ethanolate Janssen-Ortho Human immunodeficiency virus (HIV) protease inhibitor New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Tegretol carbamazepine Novartis Pharmaceuticals Anticonvulsant - Antimanic - Symptomatic relief of trigeminal neuralgia New safety information: in the adverse reactions, and warnings and precautions sections 08/15/2010
Thelin sitaxsentan sodium Pfizer Endothelin receptor antagonist New safety information: in the contraindications and adverse reactions sections 08/15/2010
Tofranil imipramine HCl Novartis Pharmaceuticals Antidepressant New safety information: in the warnings and precautions section 08/15/2010
Voltaren Ophtha diclofenac sodium Novartis Pharmaceuticals Analgesic - Anti-inflammatory New safety information: in the adverse reactions section 08/15/2010
Zocor simvastatin Merck Frosst Lipid metabolism regulator New safety information: in the warnings and precautions section 08/15/2010
Zocor simvastatin Merck Frosst Lipid metabolism regulator New indication: use in pediatric patients 10-17 years old with heterozygous familial hypercholesterolemia 08/15/2010
Adacel tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed sanofi pasteur Active immunizing agent New safety information: in the adverse reactions section 08/01/2010
CO Atorvastatin atorvastatin calcium Cobalt Lipid metabolism regulator New product 08/01/2010
Cortifoam hydrocortisone acetate Paladin Rectal anti-inflammatory corticosteroid foam Reinstated product 08/01/2010
Desferal deferoxamine mesylate Novartis Pharmaceuticals Iron and aluminum chelating agent New safety information: in the adverse reactions section 08/01/2010
EMLA lidocaine/prilocaine AstraZeneca Topical anesthetic for dermal analgesia New safety information: in the adverse reactions, and warnings and precautions sections 08/01/2010
Estalis estradiol-17β/norethindrone acetate Novartis Pharmaceuticals Estrogen - Progestin New safety information: in the adverse reactions section 08/01/2010
Finacea azelaic acid Bayer Antirosacea agent New molecular entity 08/01/2010
Ixiaro inactivated japanese encephalitis virus (attenuated strain SA14-14-2 produced in vero cells) Intercell AG Active immunizing agent New product 08/01/2010
Letrozole letrozole Cobalt Antitumor agent - Inhibitor of estrogen biosynthesis - Nonsteroidal aromatase inhibitor New product 08/01/2010
ratio-Ramipril ramipril ratiopharm Angiotensin converting enzyme inhibitor New dosage strength: 15 mg capsule 08/01/2010
Rituxan rituximab Roche Antineoplastic New safety information: in the contraindications and warnings and precautions sections 08/01/2010
Sandoz-Finasteride finasteride Sandoz Type II 5 alpha-reductase inhibitor New product 08/01/2010
Singulair montelukast sodium Merck Frosst Leukotriene receptor antagonist New safety information: in the adverse reactions, and warnings and precautions sections 08/01/2010
Statex morphine sulfate Pharmascience Opioid analgesic Reinstated product 08/01/2010
Sutent sunitinib malate Pfizer Anti-Tumour agent - Tyrosine kinase inhibitor New safety information: in the adverse reactions section 08/01/2010
Triple Antibiotic Ointment bacitracin zinc/gramicidin/polymyxin B sulfate Taro Antibiotic New product 08/01/2010
Ultram tramadol HCl Janssen-Ortho Opioid analgesic New product 08/01/2010
Victoza liraglutide Novo Nordisk Human glucagon like peptide-1 (GLP-1) New molecular entity 08/01/2010
Adcirca tadalafil Lilly cGMP-specific phosphodiesterase type 5 inhibitor New product 07/15/2010
BioGaia Chewable Tablets lactobacillus reuteri protectis Ferring Natural health product - Probiotic New product 07/15/2010
BioGaia Drops lactobacillus reuteri protectis Ferring Natural health product - Probiotic New product 07/15/2010
B-natal Lozenge pyridoxine HCl Ferring Natural health product New product 07/15/2010
B-natal Therapop vitamin B6 Ferring Natural health product New product 07/15/2010
Celebrex celecoxib Pfizer Analgesic - Anti-inflammatory New safety information: in the adverse reactions section 07/15/2010
Champix varenicline tartrate Pfizer Smoking cessation aid New safety information: in the adverse reactions, and warnings and precautions sections 07/15/2010
Effient prasugrel HCl Lilly Platelet aggregation inhibitor New molecular entity 07/15/2010
Ezetrol ezetimibe Merck Frosst-Schering Cholesterol absorption inhibitor New safety information: in the adverse reactions section 07/15/2010
GlucaGen glucagon Novo Nordisk Hyperglycemic agent New product 07/15/2010
Januvia sitagliptin phosphate Merck Frosst DPP-4 Inhibitor - Incretin enhancer - Oral antihyperglycemic agent New indication: in combination with metformin and a sulfonylurea in adult patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise, and dual therapy with these agents, do not provide adequate glycemic control 07/15/2010
Januvia sitagliptin phosphate Merck Frosst DPP-4 Inhibitor - Incretin enhancer - Oral antihyperglycemic agent New safety information: in the adverse reactions section 07/15/2010
Kytril granisetron HCl Roche Antiemetic New full monograph, previously availability only 07/15/2010
MacroBID nitrofurantoin monohydrate/macrocrystals Warner Chilcott Urinary tract antibacterial New full monograph, previously availability only 07/15/2010
Mezavant 5-ASA Shire Lower gastrointestinal anti-inflammatory New safety information: in the adverse reactions section 07/15/2010
Naprosyn naproxen Roche Nonsteroidal anti-inflammatory drug (NSAID) New full monograph, previously availability only 07/15/2010
Pepcid Tablets famotidine Merck Frosst Histamine H2-receptor antagonist New safety information: in the adverse reactions section 07/15/2010
PMS-Letrozole letrozole Pharmascience Antitumor agent - Inhibitor of estrogen biosynthesis - Nonsteroidal aromatase inhibitor New product 07/15/2010
Polyderm bacitracin zinc/polymyxin B sulfate Taro Antibiotic New product 07/15/2010
Proleukin aldesleukin Novartis Pharmaceuticals Biological response modifier New safety information: in the adverse reactions section 07/15/2010
Rilutek riluzole sanofi-aventis Antiglutamate New safety information: in the adverse reactions, and warnings and precautions sections 07/15/2010
Rythmol propafenone HCl Abbott Antiarrhythmic New full monograph, previously availability only 07/15/2010
TuZen lactobacillus plantarum 299v Ferring Natural health product - Probiotic New product 07/15/2010
Accutane Roche isotretinoin Roche Nodular/inflammatory and conglobate acne therapy New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Actemra tocilizumab Roche Interleukin receptor inhibitor New molecular entity 07/01/2010
Butrans buprenorphine Purdue Pharma Opioid analgesic New product: patch 07/01/2010
Cancidas caspofungin acetate Merck Frosst Antifungal New safety information: in the adverse reactions section 07/01/2010
Crestor rosuvastatin calcium AstraZeneca Lipid metabolism regulator New safety information: in the adverse reactions section 07/01/2010
Ebixa memantine HCl Lundbeck N-methyl-D-aspartate (NMDA) receptor New safety information: in the warnings and precautions section 07/01/2010
Erbitux cetuximab Bristol-Myers Squibb/ImClone LLC Antineoplastic New indication: for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma after failure of both irinotecan- and oxaliplatin-based regimens and who have received a fluoropyrimidine, whose tumours have a wild-type (non-mutated) Kirsten rat sarcoma (KRAS) gene 07/01/2010
Erbitux cetuximab Bristol-Myers Squibb/ImClone LLC Antineoplastic New safety information: in the adverse reactions section 07/01/2010
Humira adalimumab Abbott Biological response modifier New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Invirase saquinavir mesylate Roche Antiretroviral agent - HIV protease inhibitor New safety information: in the contraindications, warnings and precautions, adverse reactions, and drug interactions sections 07/01/2010
Isentress raltegravir potassium Merck Frosst Human immunodeficiency virus integrase strand transfer inhibitor New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Kivexa abacavir sulfate/lamivudine GlaxoSmithKline - Shire Antiretroviral agent New safety information: in the warnings and precautions section 07/01/2010
Levaquin levofloxacin Janssen-Ortho Antibacterial New safety information: in the adverse reactions section 07/01/2010
Losec Capsules omeprazole AstraZeneca H+, K+-ATPase Inhibitor New safety information: in the drug interactions section 07/01/2010
Losec Tablets omeprazole magnesium AstraZeneca H+, K+-ATPase Inhibitor New safety information: in the drug interactions section 07/01/2010
Mirena levonorgestrel Bayer Progestogen New indication: treatment of idiopathic menorrhagia following appropriate diagnostic investigation in women accepting the contraceptive effect of Mirena 07/01/2010
Mirena levonorgestrel Bayer Progestogen New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Pegetron peginterferon alfa-2b/ribavirin Schering-Plough Antiviral agent plus biological response modifier New safety information: in the adverse reactions section 07/01/2010
Priorix-Tetra measles, mumps, rubella and varicella vaccine, live, attenuated GlaxoSmithKline Active immunizing agent New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Seroquel quetiapine fumarate AstraZeneca Antipsychotic agent New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 07/01/2010
Seroquel XR quetiapine fumarate AstraZeneca Psychotropic agent New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 07/01/2010
Sprycel dasatinib Bristol-Myers Squibb Protein-tyrosine kinase inhibitor New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Suprefact buserelin acetate sanofi-aventis Luteinizing hormone-releasing hormone (LHRH) analog New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
Teva-Amlodipine amlodipine besylate Teva Canada Antianginal - Antihypertensive New product 07/01/2010
Teva-Atenolol atenolol Teva Canada Beta-adrenergic receptor blocking agent New product 07/01/2010
Teva-Citalopram citalopram HBr Teva Canada Antidepressant New product 07/01/2010
Teva-Enalapril enalapril maleate Teva Canada Angiotensin converting enzyme inhibitor New product 07/01/2010
Teva-Enalapril/HCTZ enalapril/hydrochlorothiazide Teva Canada Angiotensin converting enzyme inhibitor - Diuretic New product 07/01/2010
Teva-Ketotifen ketotifen fumarate Teva Canada Antiallergic - Pediatric asthma prophylactic New product 07/01/2010
Teva-Lansoprazole lansoprazole Teva Canada H+, K+-ATPase inhibitor New product 07/01/2010
Teva-Topiramate topiramate Teva Canada Antiepileptic - Migraine prophylaxis New Product 07/01/2010
Trizivir abacavir sulfate/lamivudine/zidovudine GlaxoSmithKline - Shire Antiretroviral agent New safety information: in the warnings and precautions section 07/01/2010
Videx EC didanosine Bristol-Myers Squibb Antiretroviral agent New safety information: in the adverse reactions, and warnings and precautions sections 07/01/2010
HMG-CoA Reductase Inhibitors atorvastatin calcium/fluvastatin sodium/lovastatin/pravastatin sodium/rosuvastatin calcium/simvastatin CPhA Monograph Lipid metabolism regulator - Statins Completely updated monograph 06/15/2010
Afinitor everolimus Novartis Pharmaceuticals Antineoplastic agent (mTOR kinase inhibitor) New molecular entity 06/15/2010
Apo-Atorvastatin atorvastatin calcium Apotex Lipid metabolism regulator New product 06/15/2010
Azarga brinzolamide/timolol maleate Alcon Elevated intraocular pressure therapy New product 06/15/2010
Cholestyramine cholestyramine resin CPhA Monograph Antidiarrheal - Antihypercholesterolemic - Bile acid sequestrant Completely updated monograph 06/15/2010
CO Memantine memantine HCl Cobalt N-methyl-D-aspartate (NMDA) receptor antagonist New product 06/15/2010
Cosopt dorzolamide HCl/timolol maleate Merck Frosst Elevated intraocular pressure therapy New safety information: in the adverse reactions, and warnings and precautions sections 06/15/2010
Florastor Saccharomyces boulardii lyo Medical Futures Natural health product New product 06/15/2010
Teva-Atorvastatin atorvastatin calcium Teva Canada Lipid metabolism regulator New product 06/15/2010
Nozinan methotrimeprazine HCl sanofi-aventis Neuroleptic New safety information: in the adverse reactions, and warnings and precautions sections 06/15/2010
PMS-Atorvastatin atorvastatin calcium Pharmascience Lipid metabolism regulator New product 06/15/2010
Proferrin heme iron polypeptide Medical Futures Natural health product New product 06/15/2010
RAN-Atorvastatin atorvastatin calcium Ranbaxy Lipid metabolism regulator New product 06/15/2010
ratio-Atorvastatin atorvastatin calcium ratiopharm Lipid metabolism regulator New product 06/15/2010
Suprefact Depot buserelin acetate sanofi-aventis Luteinizing hormone-releasing hormone (LHRH) analog New safety information: in the adverse reactions section 06/15/2010
Topamax topiramate Janssen-Ortho Antiepileptic - Migraine prophylaxis New safety information: in the warnings and precautions section 06/15/2010
Androcur/Androcur Depot cyproterone acetate Bayer Antiandrogen New safety information: in the adverse reactions section 06/01/2010
AndroGel testosterone Solvay Pharma Androgens New safety information: in the adverse reactions, and warnings and precautions sections 06/01/2010
CellCept mycophenolate mofetil Roche Immunosuppressant New safety information: in the adverse reactions, and warnings and precautions sections 06/01/2010
COLD-FX North American ginseng (Panax quinquefolius) Afexa Life Sciences Natural health product New dosage strength: 300 mg capsule 06/01/2010
CO Olanzapine olanzapine Cobalt Antipsychotic New product 06/01/2010
CO Olanzapine ODT olanzapine Cobalt Antipsychotic New product 06/01/2010
Doribax doripenem Janssen-Ortho Antibacterial New safety information: in the adverse reactions section 06/01/2010
Enbrel etanercept Amgen Biological response modifier New safety information: in the adverse reactions, and warnings and precautions sections 06/01/2010
Extavia interferon beta-1b Novartis Pharmaceuticals Immunomodulator New molecular entity 06/01/2010
Ilaris canakinumab Novartis Pharmaceuticals Immunomodulatory Agent New molecular entity 06/01/2010
Micatin miconazole nitrate WellSpring Topical antifungal Reinstated product 06/01/2010
Pegasys peginterferon alfa-2a Roche Biological response modifier New safety information: in the adverse reactions, and warnings and precautions sections 06/01/2010
Pegasys RBV peginterferon alfa-2a/ribavirin Roche Antiviral agent - Biological response modifier New safety information: in the adverse reactions, and warnings and precautions sections 06/01/2010
Rebif interferon beta-1a EMD Serono Immunomodulator New safety information: in the adverse reactions section 06/01/2010
Toloxin digoxin MM Therapeutics Cardiotonic glycoside New product 06/01/2010
Zometa Concentrate zoledronic acid Novartis Pharmaceuticals Bone metabolism regulator New safety information: in the adverse reactions section 06/01/2010
Apidra insulin glulisine (recombinant DNA origin) sanofi-aventis Antidiabetic agent New indication: extension of the indication to include pediatric population 6 years and older 05/15/2010
Apidra insulin glulisine (recombinant DNA origin) sanofi-aventis Antidiabetic agent New safety information: in the adverse reactions, and warnings and precautions sections 05/15/2010
Apo-Granisetron granisetron HCl Apotex 5-HT3 receptor antagonist - Antiemetic New product 05/15/2010
Avastin bevacizumab Roche Antineoplastic New indication: as a single agent, for the treatment of patients with glioblastoma after relapse or disease progression, following prior therapy 05/15/2010
BeneFIX coagulation factor IX (recombinant) (nonacog alfa) Wyeth Canada Antihemorrhagic blood boagulation factor IX New safety information: in the adverse reactions section 05/15/2010
Crestor rosuvastatin calcium AstraZeneca Lipid metabolism regulator New indication: use in pediatric patients 10-17 years old with heterozygous familial hypercholesterolemia 05/15/2010
Cubicin daptomycin Sepracor Antibacterial New safety information: in the warnings and precautions section 05/15/2010
Emend IV fosaprepitant Merck Frosst Neurokinin 1 (NK1) receptor antagonist New safety information: in the adverse reactions, and warnings and precautions sections 05/15/2010
Firmagon degarelix acetate Ferring Gonadotropin-releasing hormone receptor antagonist New molecular entity 05/15/2010
Lasix Special furosemide sanofi-aventis Diuretic New safety information: in the warnings and precautions and drug interactions sections 05/15/2010
Rasilez aliskiren fumarate Novartis Pharmaceuticals Renin inhibitor New safety information: in the drug interactions section 05/15/2010
Rasilez HCT aliskiren fumarate/hydrochlorothiazide Novartis Pharmaceuticals Diuretic - Renin inhibitor New Product 05/15/2010
Risperdal Consta risperidone Janssen-Ortho Antipsychotic New indication: bipolar disorder - as monotherapy maintenance treatment in patients with bipolar 1 disorder to delay occurrence of manic episodes 05/15/2010
Risperdal Consta risperidone Janssen-Ortho Antipsychotic New safety information: in the warnings and precautions section 05/15/2010
Sandoz-Letrozole letrozole Sandoz Antitumor agent - Inhibitor of estrogen biosynthesis - Nonsteroidal aromatase inhibitor New product issued under the NOC/C Policy 05/15/2010
Simponi golimumab Centocor Tumour necrosis factor alpha (TNFα) inhibitor New safety information: in the warnings and precautions and drug interactions sections 05/15/2010
Stalevo carbidopa/entacapone/levodopa Novartis Pharmaceuticals Anti-parkinsonian dopaminergic agent New dosage strengths: 75/18.75/200 mg and 125/31.25/200 mg tablets 05/15/2010
Xolair omalizumab Novartis Pharmaceuticals IgE-neutralizing antibody (Anti-IgE) New safety information: in the adverse reactions, and warnings and precautions sections 05/15/2010
Yasmin drospirenone/ethinyl estradiol Bayer Oral contraception New safety information: in the adverse reactions section 05/15/2010
Zavesca miglustat Actelion Glucosylceramide synthase inhibitor New indication: to slow the progression of some of the neurological manifestations in patients with Niemann-Pick type C disease 05/15/2010
Zavesca miglustat Actelion Glucosylceramide synthase inhibitor New safety information: in the adverse reactions, and warnings and precautions sections 05/15/2010
Vitamin K phytonadione CPhA monograph Hypoprothrombinemia therapy Completely updated monograph 05/01/2010
Cayston aztreonam Gilead Sciences Antibiotic New molecular entity 05/01/2010
Celsentri maraviroc Pfizer CCR5 antagonist New indication: use in treatment-naive patients infected with CCR5-tropic HIV-1 05/01/2010
Cervarix recombinant human papillomavirus type 16 L1 protein /recombinant human papillomavirus type 18 L1 protein GlaxoSmithKline Active immunizing agent New product 05/01/2010
Emend aprepitant Merck Frosst Neurokinin 1 (NK1) receptor antagonist New safety information: in the adverse reactions section 05/01/2010
Forteo teriparatide (rDNA origin) Lilly Bone formation agent New safety information: in the adverse reactions, and warnings and precautions sections 05/01/2010
Heparin: Unfractionated heparin sodium CPhA monograph Anticoagulant Completely updated monograph 05/01/2010
Monovisc sodium hyaluronate Helix Biopharma Synovial fluid replacement/replenishment New product 05/01/2010
Prevnar 13 pneumococcal 13-valent conjugate vaccine (diphtheria CRM197 protein) Wyeth Canada Active immunizing agent New product 05/01/2010
Prezista darunavir ethanolate Janssen-Ortho Human immunodeficiency virus (HIV) protease inhibitor New indication: extension of the indication to include pediatric population 6 years and older 05/01/2010
Prezista darunavir ethanolate Janssen-Ortho Human immunodeficiency virus (HIV) protease inhibitor New dosage strength: 75 mg tablets for the pediatric patient population 05/01/2010
Primovist gadoxetate disodium Bayer Intravenous contrast enhancement agent for magnetic resonance imaging (MRI) New product 05/01/2010
Recothrom thrombin alfa (recombinant) Bayer Coagulation factor New product 05/01/2010
Sustiva efavirenz Bristol-Myers Squibb Antiretroviral agent New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 05/01/2010
Tysabri natalizumab Biogen Idec Selective adhesion molecule inhibitor New safety information: in the adverse reactions section 05/01/2010
Vaniqa eflornithine HCl Triton Pharma Hair growth inhibitor Reinstated product 05/01/2010
Vfend voriconazole Pfizer Antifungal New safety information: in the drug interactions section 05/01/2010
Vibramycin doxycycline hyclate Pfizer Antibiotic New safety information: in the adverse reactions, and warnings and precautions sections 05/01/2010
Vyvanse lisdexamfetamine dimesylate Shire Central nervous system stimulant for attention deficit hyperactivity disorder New dosage strengths: 20 mg, 40 mg, and 60 mg tablets 05/01/2010
Xyrem sodium oxybate Valeant CNS depressant New safety information: in the adverse reactions section 05/01/2010
Apo-Sibutramine sibutramine HCl monohydrate Apotex Anorexiant -Antiobesity agent New product 04/15/2010
Arthrotec diclofenac sodium/misoprostol Pfizer Mucosal protective agent - NSAID New safety information: in the drug interactions and adverse reactions sections 04/15/2010
Crestor rosuvastatin calcium AstraZeneca Lipid metabolism regulator New indication: To reduce the risk of non-fatal myocardial infarction or stroke, or coronary revascularization in patients without documented cardiovascular events but with at least two risk factors for cardiovascular disease 04/15/2010
Crestor rosuvastatin calcium AstraZeneca Lipid metabolism regulator New safety information: in the adverse reactions section 04/15/2010
Emend aprepitant Merck Frosst Neurokinin 1 (NK1) receptor antagonist Revised indication: prevention of nausea and vomiting in women due to treatment with moderately emetogenic cancer chemotherapy 04/15/2010
Emend IV fosaprepitant Merck Frosst Neurokinin 1 (NK1) receptor antagonist Revised indication: prevention of nausea and vomiting in women due to treatment with moderately emetogenic cancer chemotherapy 04/15/2010
Mirena levonorgestrel Bayer Progestogen New safety information: in the warnings and precautions and adverse reactions sections 04/15/2010
PMS-Finasteride finasteride Pharmascience Type II 5 alpha-reductase inhibitor New product 04/15/2010
Prinzide hydrochlorothiazide/lisinopril Merck Frosst Angiotensin converting enzyme inhibitor - Diuretic New safety information: in the drug interactions section 04/15/2010
ratio-Finasteride finasteride ratiopharm Type II 5 alpha-reductase inhibitor New product 04/15/2010
Travatan travoprost Alcon Elevated intraocular pressure therapy - Prostaglandin F2α analogue New safety information: in the adverse reactions section 04/15/2010
Vasotec enalapril Merck Frosst Angiotensin converting enzyme inhibitor New safety information: in the drug interactions section 04/15/2010
Endometrin progesterone Ferring Progestin New product: vaginal effervescent tablets 04/01/2010
Jurnista hydromorphone HCl Janssen-Ortho Opioid analgesic New product 04/01/2010
Allegra-D fexofenadine HCl/pseudoephedrine HCl sanofi-aventis Histamine H1-receptor antagonist - Sympathomimetic amine New safety information: in the adverse reactions section 04/01/2010
Alvesco ciclesonide Altana Corticosteroid for oral inhalation New safety information: in the adverse reactions section 04/01/2010
Ansaid flurbiprofen Pfizer Nonsteroidal anti-inflammatory drug (NSAID) New safety information: in the drug interactions section 04/01/2010
Apo-Tramadol/Acet acetaminophen/tramadol HCl Apotex Centrally acting analgesic New product 04/01/2010
Children's Motrin Cold ibuprofen/pseudoephedrine HCl McNeil Consumer Healthcare Analgesic - Antipyretic - Decongestant New product 04/01/2010
Cyclen ethinyl estradiol/norgestimate Janssen-Ortho Oral contraceptive New safety information: in the contraindications, drug interactions, and adverse reactions sections 04/01/2010
Duragesic Mat fentanyl Janssen-Ortho Opioid analgesic New safety information: in the drug interactions section 04/01/2010
Nitrates isosorbide dinitrate/isosorbide-5-mononitrate/nitroglycerin CPhA Monograph Antianginal - Antihypertensive Completely updated monograph 04/01/2010
Pegetron peginterferon alfa-2b/ribavirin Schering-Plough Antiviral agent plus biological response modifier New dosing and extension of indication: treatment of adult patients (18 years of age and older) with chronic hepatitis C who have compensated liver disease and are positive for HCV-RNA, including patients who have not received previous treatment or who failed prior treatment with interferon alpha (pegylated or non-pegylated) and ribavirin combination therapy 04/01/2010
Premarin Vaginal Cream conjugated estrogens Wyeth Canada Estrogenic hormones New safety information: in the adverse reactions, and warnings and precautions sections 04/01/2010
Provera medroxyprogesterone acetate Pfizer Progestin New safety information: in the adverse reactions, and warnings and precautions sections 04/01/2010
Rasilez aliskiren fumarate Novartis Pharmaceuticals Renin inhibitor New indication: concomitant use with angiotensin II ATI receptor blockers 04/01/2010
ratio-Rivastigmine rivastigmine hydrogen tartrate ratiopharm Cholinesterase inhibitor New product 04/01/2010
Taxol paclitaxel Bristol-Myers Squibb Antineoplastic New safety information: in the adverse reactions, and warnings and precautions sections 04/01/2010
Tri-Cyclen ethinyl estradiol/norgestimate Janssen-Ortho Oral contraceptive New safety information: in the contraindications, drug interactions, and adverse reactions sections 04/01/2010
Trileptal oxcarbazepine Novartis Pharmaceuticals Antiepileptic New safety information: in the warnings and precautions section 04/01/2010
Vectibix panitumumab Amgen Antineoplastic New safety information: in the adverse reactions section 04/01/2010
Zeftera ceftobiprole medocaril Janssen-Ortho Antibacterial agent New safety information: in the adverse reactions section 04/01/2010
Zestoretic hydrochlorothiazide/lisinopril AstraZeneca Angiotensin converting enzyme inhibitor - Diuretic New safety information: in the drug interactions and adverse reactions sections 04/01/2010
Zevalin ibritumomab tiuxetan Bayer Therapeutic radiopharmaceutical New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 04/01/2010
Adriamycin PFS doxorubicin HCl Pfizer Antineoplastic New safety information: in the drug interactions section 03/15/2010
Altace ramipril sanofi-aventis Angiotensin converting enzyme inhibitor New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 03/15/2010
Arimidex anastrozole AstraZeneca Nonsteroidal aromatase inhibitor New safety information: in the adverse reactions section 03/15/2010
Cyclomen danazol sanofi-aventis Pituitary gonadotropin inhibitor New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 03/15/2010
Fosrenol lanthanum carbonate hydrate Shire Phosphate binder New safety information: in the drug interactions section 03/15/2010
Lasix furosemide sanofi-aventis Diuretic New safety information: in the warnings and precautions and drug interactions sections 03/15/2010
Magnevist gadopentetate dimeglumine Bayer Contrast enhancement agent for magnetic resonance imaging (MRI) New safety information: in the adverse reactions section 03/15/2010
Maxalt rizatriptan benzoate Merck Frosst Migraine therapy New safety information: in the adverse reactions section 03/15/2010
Neurontin gabapentin Pfizer Antiepileptic New safety information: in the adverse reactions section 03/15/2010
Nexavar sorafenib Bayer Antineoplastic - Multikinase inhibitor New safety information: in the adverse reactions section 03/15/2010
Nitoman tetrabenazine Biovail Pharmaceuticals Monoamine depleting agent New safety information: in the drug interactions section 03/15/2010
Orencia abatacept Bristol-Myers Squibb Selective co-stimulation modulator New indication: when used as first-line treatment in recently diagnosed patients who have not been previously treated with Methotrexate (MTX), Orencia should be given in combination with MTX 03/15/2010
Orencia abatacept Bristol-Myers Squibb Selective co-stimulation modulator New safety information: in the adverse reactions section 03/15/2010
Ortho-Cept desogestrel/ethinyl estradiol Janssen-Ortho Oral contraceptive New safety information: in the drug interactions and adverse reactions sections 03/15/2010
Premarin Tablets conjugated estrogens Wyeth Canada Estrogenic hormones New safety information: in the adverse reactions, and warnings and precautions sections 03/15/2010
RotaTeq rotavirus vaccine, live, oral, pentavalent Merck Frosst Live, oral pentavalent vaccine against rotavirus gastroenteritis New safety information: in the warnings and precautions section 03/15/2010
Taxotere docetaxel sanofi-aventis Antineoplastic New safety information: in the adverse reactions, and warnings and precautions sections 03/15/2010
Tracleer bosentan Actelion Endothelin receptor antagonist New safety information: in the drug interactions section 03/15/2010
Zestril lisinopril AstraZeneca Angiotensin converting enzyme inhibitor New safety information: in the drug interactions and adverse reactions sections 03/15/2010
Zyclara imiquimod Graceway Immune response modifier New product 03/15/2010
Avelox, Avelox IV moxifloxacin HCl Bayer Antibacterial agent New safety information: in the warnings and precautions section 03/01/2010
Intelence etravirine Janssen-Ortho Human immunodeficiency virus (HIV) non-nucleoside reverse transcriptase inhibitor New safety information: in the adverse reactions section 03/01/2010
Micardis telmisartan Boehringer Ingelheim Angiotensin II AT1 receptor blocker New indication: risk reduction of cardiovascular morbidity in patients intolerant to angiotensin converting enzyme inhibitors 03/01/2010
Micardis telmisartan Boehringer Ingelheim Angiotensin II AT1 receptor blocker New safety information: in the drug interactions and adverse reactions sections 03/01/2010
Odan K-20 potassium chloride Odan Potassium supplement New product 03/01/2010
PMS-Testosterone testosterone undecanoate Pharmascience Androgen New product 03/01/2010
Prograf tacrolimus Astellas Immunosuppressant New safety information: in the adverse reactions section 03/01/2010
Sandostatin/Sandostatin LAR octreotide acetate Novartis Pharmaceuticals Synthetic octapeptide analogue of somatostatin New safety information: in the adverse reactions section 03/01/2010
Sensipar cinacalcet HCl Amgen Calcimimetic agent New safety information: in the adverse reactions section 03/01/2010
Tarceva erlotinib HCl Roche Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor New safety information: in the warnings and precautions and adverse reactions sections 03/01/2010
Velcade bortezomib mannitol boronic ester Janssen-Ortho Antineoplastic agent New safety information: in the adverse reactions section 03/01/2010
Xeloda capecitabine Roche Antineoplastic New safety information: in the drug interactions and adverse reactions sections 03/01/2010
Xeloda capecitabine Roche Antineoplastic New indication: in combination with oxaliplatin for the treatment of metastatic colorectal cancer following failure of irinotecan-containing combination chemotherapy 03/01/2010
Xenical orlistat Roche Antiobesity - Gastrointestinal lipase inhibitor New safety information: in the warnings and precautions and drug interactions sections 03/01/2010
Vyvanse lisdexamfetamine dimesylate Shire Central nervous system stimulant for attention deficit hyperactivity disorder New molecular entity 02/15/2010
Aclasta zoledronic acid Novartis Pharmaceuticals Bone metabolism regulator New indication: the prevention of postmenopausal osteoporosis in women with osteopenia as a single intravenous infusion 02/15/2010
Aclasta zoledronic acid Novartis Pharmaceuticals Bone metabolism regulator New safety information: in the adverse reactions section 02/15/2010
Adderall XR mixed salts amphetamine Shire CNS stimulant New safety information: in the drug interactions section 02/15/2010
Avodart dutasteride GlaxoSmithKline Type I and II 5 alpha-reductase inhibitor New indication: use in combination with tamsulosin for the treatment of moderate to severe symptomatic Benign Prostatic Hyperplasia (BPH) in men with enlarged prostates 02/15/2010
Besivance besifloxacin Bausch & Lomb Antibacterial (ophthalmic) New molecular entity 02/15/2010
Flagyl metronidazole sanofi-aventis Antibacterial - Antiprotozoal New safety information: in the adverse reactions section 02/15/2010
GD-amlodipine amlodipine besylate GenMed Antianginal - Antihypertensive New product 02/15/2010
Gleevec imatinib mesylate Novartis Pharmaceuticals Protein kinase inhibitor New indication: for the adjuvant treatment of adult patients who are at intermediate to high risk of relapse following complete resection of Kit (CD117) positive GIST 02/15/2010
Hepsera adefovir dipivoxil Gilead Sciences Antiviral agent New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 02/15/2010
Januvia sitagliptin phosphate Merck Frosst DPP-4 Inhibitor - Incretin enhancer - Oral antihyperglycemic agent New indication: monotherapy - as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes mellitus and for whom metformin is inappropriate due to contraindications or intolerance 02/15/2010
Teva-Methylphenidate ER-C methylphenidate HCl Teva Canada CNS Stimulant New product 02/15/2010
Teva-Risedronate risedronate sodium monohydrate Teva Canada Bone metabolism regulator New product 02/15/2010
Teva-Salbutamol HFA salbutamol sulphate Teva Canada Bronchodilator New product 02/15/2010
Onglyza saxagliptin HCl Bristol-Myers Squibb DPP-4 inhibitor - Incretin enhancer - Oral antihyperglycemic agent New molecular entity 02/15/2010
RAN-Amlodipine amlodipine besylate Ranbaxy Antianginal - Antihypertensive New product 02/15/2010
RAN-Ramipril ramipril Ranbaxy Angiotensin converting enzyme inhibitor New product 02/15/2010
RAN-Ropinirole ropinirole HCl Ranbaxy Antiparkinsonian agent - Dopamine agonist New product 02/15/2010
RAN-Simvastatin simvastatin Ranbaxy Lipid metabolism regulator New product 02/15/2010
Topotecan for Injection topotecan HCl Sandoz Antineoplastic New product 02/15/2010
Atripla efavirenz/emtricitabine/tenofovir disoproxil fumarate Gilead Sciences Antiretroviral agent New safety information: in the warnings and precautions, adverse reactions, and drug interactions sections 02/01/2010
Camptosar irinotecan HCl trihydrate Pfizer Antineoplastic New safety information: in the warnings and precautions, adverse reactions sections 02/01/2010
Plavix clopidogrel bisulfate sanofi-aventis Platelet aggregation inhibitor New safety information: in the warnings and precautions and drug interactions sections 02/01/2010
Iressa gefitinib AstraZeneca Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor New indication: for the first line treatment of patients with locally advanced (not amenable to curative therapy) or metastatic non-small cell lung cancer (NSCLC) who have activating mutations of the EGFR-TK 02/01/2010
Acetylcysteine Injection acetylcysteine Alveda Antidote for acetaminophen poisoning - Mucolytic New product 01/15/2010
Enbrel etanercept Amgen Biological response modifier New safety information: in the drug interactions and adverse reactions sections 01/15/2010
Hydralazine hydralazine CPhA monograph Antihypertensive - Vasodilator Completely updated monograph 01/15/2010
Propranolol propranolol HCl CPhA monograph Beta-adrenergic receptor blocking agent, nonselective Completely updated monograph 01/15/2010
Salazopyrin/Salazopyrin EN-tabs sulfasalazine Pfizer Anti-inflammatory New safety information: in the adverse reactions section 01/15/2010
Avamys fluticasone furoate GlaxoSmithKline Corticosteroid for nasal use New indication: treatment of perennial allergic rhinitis in pediatrics (2 years to < 12 years of age) 12/15/2009
Lamictal lamotrigine GlaxoSmithKline Antiepileptic New safety information: in the adverse reactions, and warnings and precautions sections 12/15/2009
Methylene Blue Injection methylene blue Alveda Antidote New product 12/15/2009
Teva-Naratriptan naratriptan HCl Teva Canada 5-HT1 receptor agonist - Migraine therapy New product 12/15/2009
Priorix-Tetra measles, mumps, rubella and varicella vaccine, live, attenuated GlaxoSmithKline Active immunizing agent New indication: active immunization against measles, mumps, rubella and varicella in individuals from 9 to 24 months of age. 12/15/2009
Relenza zanamivir GlaxoSmithKline Antiviral agent New safety information: in the adverse reactions, and warnings and precautions sections 12/15/2009
Sodium Chloride Injection sodium chloride Alveda Diluent New product 12/15/2009
Sterile Water for Injection water Alveda Diluent New product 12/15/2009
Tamiflu oseltamivir phosphate Roche Antiviral agent New product information: updated directions for emergency compounding 12/15/2009
Taro-Mometasone Lotion mometasone furoate Taro Corticosteroid New product 12/15/2009